Author: Wang, Shiliang; Sundaram, Jaideep P; Spiro, David
Title: VIGOR, an annotation program for small viral genomes Document date: 2010_9_7
ID: 0lbxvudt_46
Snippet: AY485277 is another SARS coronavirus genome that has 8 ORFs annotated in GenBank [27] . VIGOR predicted an additional 7 ORFs (Table 3 ). These 7 ORFs were corroborated by comparing them with other viral proteins in GenBank. ZCURVE_V detected 12 ORFs including 5 ORFs which were not annotated in Gen-Bank; these 5 ORFs are highly homologous to other viral proteins. One ORF annotated in GenBank and two ORFs predicted by VIGOR were ignored by ZCUR-VE_.....
Document: AY485277 is another SARS coronavirus genome that has 8 ORFs annotated in GenBank [27] . VIGOR predicted an additional 7 ORFs (Table 3 ). These 7 ORFs were corroborated by comparing them with other viral proteins in GenBank. ZCURVE_V detected 12 ORFs including 5 ORFs which were not annotated in Gen-Bank; these 5 ORFs are highly homologous to other viral proteins. One ORF annotated in GenBank and two ORFs predicted by VIGOR were ignored by ZCUR-VE_V. GeneMarkS identified 9 ORFs. Three GenBank annotated genes were missing, and 3 VIGOR predictions were also missing from the GeneMarkS prediction list. Neither GeneMarkS nor ZCURVE_V predicted orf1ab protein correctly.
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