Author: Paesen, Guido C.; Collet, Axelle; Sallamand, Corinne; Debart, Françoise; Vasseur, Jean-Jacques; Canard, Bruno; Decroly, Etienne; Grimes, Jonathan M.
Title: X-ray structure and activities of an essential Mononegavirales L-protein domain Document date: 2015_11_9
ID: 1taxqkk2_11
Snippet: The absence of a classical cap-binding site. A common feature of MTases involved in cap methylation is a defined cap-binding pocket that binds G with high affinity, enabling subsequent, lowaffinity interactions with the triphosphate bridge and the first few nucleotides, thus precluding methylation of uncapped RNAs 15, 16 ......
Document: The absence of a classical cap-binding site. A common feature of MTases involved in cap methylation is a defined cap-binding pocket that binds G with high affinity, enabling subsequent, lowaffinity interactions with the triphosphate bridge and the first few nucleotides, thus precluding methylation of uncapped RNAs 15, 16 .
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