Author: He, Biao; Li, Zuosheng; Yang, Fanli; Zheng, Junfeng; Feng, Ye; Guo, Huancheng; Li, Yingying; Wang, Yiyin; Su, Nan; Zhang, Fuqiang; Fan, Quanshui; Tu, Changchun
Title: Virome Profiling of Bats from Myanmar by Metagenomic Analysis of Tissue Samples Reveals More Novel Mammalian Viruses Document date: 2013_4_22
ID: 04d0koah_45
Snippet: Members of family Hepadnaviridae have a compact circular genome and comprise two genera, Orthohepadnavirus and Avihepad-navirus, the former infecting several mammalian species including humans, woodchucks, and ground squirrels [48] . In our study, .10,000 hepadnavirus-like contigs were detected in all four groups through viral metagenomics, showing ,70% nt identity with woodchuck hepatitis virus (WHV) and HBV ( Table 3 ). The 423 bp amplicons of .....
Document: Members of family Hepadnaviridae have a compact circular genome and comprise two genera, Orthohepadnavirus and Avihepad-navirus, the former infecting several mammalian species including humans, woodchucks, and ground squirrels [48] . In our study, .10,000 hepadnavirus-like contigs were detected in all four groups through viral metagenomics, showing ,70% nt identity with woodchuck hepatitis virus (WHV) and HBV ( Table 3 ). The 423 bp amplicons of partial S genes of 7 selected bat hepadnaviruses showed .97% nucleotide identity with each other, 77% nucleotide identity with WHV and 74% with HBV (Figure 7) , indicating that the bat hepadnavirus found in the study is likely a new orthohepadnavirus.
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