Selected article for: "PANDO histopathology and present study"
Author: Yanik, Özge; Hosal, Banu; Tekeli, Alper; Nalci, Hilal
Title: Viral nucleic acid analysis with PCR in lacrimal tissue and nasal swab samples of primary acquired nasolacrimal duct obstruction cases
  • Document date: 2019_10_21
    • ID: 1embrj6v_20
    Snippet: PANDO is the most common cause of acquired nasolacrimal duct obstruction in the adult. 3 The exact mechanisms leading to chronic inflammation and secondary fibrosis, which are the predominant findings of the PANDO histopathology, [2] [3] [4] have not yet been elucidated. The only previous study that evaluated the viral presence in PANDO was performed by Kashkouli et al. 14 They examined the biopsy specimens of 51 PANDO cases for the presence of h.....
    Document: PANDO is the most common cause of acquired nasolacrimal duct obstruction in the adult. 3 The exact mechanisms leading to chronic inflammation and secondary fibrosis, which are the predominant findings of the PANDO histopathology, [2] [3] [4] have not yet been elucidated. The only previous study that evaluated the viral presence in PANDO was performed by Kashkouli et al. 14 They examined the biopsy specimens of 51 PANDO cases for the presence of herpes simplex virus 1, herpes simplex virus 2, and human papillomavirus. However, the immunohistochemistry results were negative for the viruses in all the cases. To the best of our knowledge, the present study was the first to report the presence of respiratory viral genomes directly in the proximal nasolacrimal duct mucosa of four patients with PANDO.

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