Author: He, Biao; Li, Zuosheng; Yang, Fanli; Zheng, Junfeng; Feng, Ye; Guo, Huancheng; Li, Yingying; Wang, Yiyin; Su, Nan; Zhang, Fuqiang; Fan, Quanshui; Tu, Changchun
Title: Virome Profiling of Bats from Myanmar by Metagenomic Analysis of Tissue Samples Reveals More Novel Mammalian Viruses Document date: 2013_4_22
ID: 04d0koah_47
Snippet: Bats are the natural host of a large variety of mammalian viruses and play an important role in the transmission of many emerging or re-emerging viral diseases to humans and animals from their natural habitats. By 2007, more than 60 bat-borne viruses had been identified globally by traditional virologic methods. This required several decades and the work of numerous laboratories [2, 57] . With metagenomic analysis based on next generation sequenc.....
Document: Bats are the natural host of a large variety of mammalian viruses and play an important role in the transmission of many emerging or re-emerging viral diseases to humans and animals from their natural habitats. By 2007, more than 60 bat-borne viruses had been identified globally by traditional virologic methods. This required several decades and the work of numerous laboratories [2, 57] . With metagenomic analysis based on next generation sequencing and high throughput screening, the frequency of discovering new bat viruses has rapidly increased and more than 20 new mammalian viruses or distantly related variants of known mammalian viruses, along with a number of unknown viruses, have been identified in last two or three years by a few laboratories. In addition, the virome constitution of bats has been elucidated by this modern technology [10, [35] [36] [37] . Using this tool, the present study has revealed a virome of Myanmar bats, comprising 24 viral families capable of infecting vertebrates, insects, plants or bacteria. Sequence comparisons here have uncovered new viruses, further expanding the range of virus composition in the bat population.
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