Author: Wang, Shiliang; Sundaram, Jaideep P; Spiro, David
Title: VIGOR, an annotation program for small viral genomes Document date: 2010_9_7
ID: 0lbxvudt_40
Snippet: Coronavirus genomes are 27 to 31 Kb in size and encode 9-15 proteins. The genomic structure of each species in the coronavirus genus is highly variable [6] with considerable species diversity among the non-structural proteins. The first open reading frame occupies about 2/3 of the genome, and ribosomal slippage occurs in the expression of this transcript, producing two polypeptides (orf1a and orf1ab) which are cleaved into functional mature pepti.....
Document: Coronavirus genomes are 27 to 31 Kb in size and encode 9-15 proteins. The genomic structure of each species in the coronavirus genus is highly variable [6] with considerable species diversity among the non-structural proteins. The first open reading frame occupies about 2/3 of the genome, and ribosomal slippage occurs in the expression of this transcript, producing two polypeptides (orf1a and orf1ab) which are cleaved into functional mature peptides. Coronavirus genomes also encode overlapping genes and genes which are completely embedded within other genes.
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