Selected article for: "copy number and relative copy number"
Author: Joshua A. Hayward; Mary Tachedjian; Adam Johnson; Tamsin B. Gordon; Jie Cui; Glenn A. Marsh; Michelle L. Baker; Lin-Fa Wang; Gilda Tachedjian
Title: Bats Possess Unique Variants of the Antiviral Restriction Factor Tetherin
  • Document date: 2020_4_9
    • ID: eksi9yia_1
    Snippet: Bats are reservoirs of viruses that are highly pathogenic to other mammals, including humans. Viruses such as Hendra, Nipah, Ebola, Marburg, severe acute respiratory syndrome coronaviruses (SARS-CoV-1 and likely also SARS-CoV-2), and the Sosuga virus have crossed species barriers from bats into humans (1) (2) (3) (4) . Laboratory studies demonstrate that specific bat species can be infected with Ebola, Marburg, SARS-CoV-1, Hendra, and Nipah virus.....
    Document: Bats are reservoirs of viruses that are highly pathogenic to other mammals, including humans. Viruses such as Hendra, Nipah, Ebola, Marburg, severe acute respiratory syndrome coronaviruses (SARS-CoV-1 and likely also SARS-CoV-2), and the Sosuga virus have crossed species barriers from bats into humans (1) (2) (3) (4) . Laboratory studies demonstrate that specific bat species can be infected with Ebola, Marburg, SARS-CoV-1, Hendra, and Nipah viruses without showing clinical symptoms (5) (6) (7) (8) (9) . Recently, this has led to efforts to elucidate if there are differences observed between the antiviral strategies of bats and other mammals (10) (11) (12) (13) (14) (15) (16) . These studies have identified that genes related to immunity in bats are under a significant degree of positive selection, in addition to differences in the copy number and diversity of innate immune genes of bats relative to other mammals (11) (12) (13) (14) 16) .

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