Selected article for: "mrna level and protein level"

Author: Laneve, Pietro; Piacentini, Lucia; Casale, Assunta Maria; Capauto, Davide; Gioia, Ubaldo; Cappucci, Ugo; Di Carlo, Valerio; Bozzoni, Irene; Di Micco, Patrizio; Morea, Veronica; Di Franco, Carmela Antonia; Caffarelli, Elisa
Title: Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration
  • Document date: 2017_1_31
  • ID: 1rw05x6m_22
    Snippet: Indeed, dendoU pan-neuronal silencing resulted in 35% decrease of dTDP-43 protein in late pupal heads and thoracic-abdominal ganglia, compared to control (Fig. 5f ). However, dTDP-43 mRNA levels showed no alteration (Fig. 5g) . These results were confirmed by the analysis of the second dendoU RNAi line, which showed a comparable decrease of dTDP-43 protein without any alteration of mRNA level ( Supplementary Fig. 6a,b) ......
    Document: Indeed, dendoU pan-neuronal silencing resulted in 35% decrease of dTDP-43 protein in late pupal heads and thoracic-abdominal ganglia, compared to control (Fig. 5f ). However, dTDP-43 mRNA levels showed no alteration (Fig. 5g) . These results were confirmed by the analysis of the second dendoU RNAi line, which showed a comparable decrease of dTDP-43 protein without any alteration of mRNA level ( Supplementary Fig. 6a,b) .

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