Author: Laneve, Pietro; Piacentini, Lucia; Casale, Assunta Maria; Capauto, Davide; Gioia, Ubaldo; Cappucci, Ugo; Di Carlo, Valerio; Bozzoni, Irene; Di Micco, Patrizio; Morea, Veronica; Di Franco, Carmela Antonia; Caffarelli, Elisa
Title: Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration Document date: 2017_1_31
ID: 1rw05x6m_30
Snippet: A multiple sequence alignment comprising all the matched sequences was produced using a local version of ClustalW 27 (http://www.clustal.org/). This alignment was edited using the Bioedit 7.2.5 package (http://www. mbio.ncsu.edu/bioedit/bioedit.html) to retain only sequences where the three XendoU residues whose point mutation abolished catalysis (i.e., H162, H178, K224) are present. The alignment shown in Supplementary Table 1 was edited by hand.....
Document: A multiple sequence alignment comprising all the matched sequences was produced using a local version of ClustalW 27 (http://www.clustal.org/). This alignment was edited using the Bioedit 7.2.5 package (http://www. mbio.ncsu.edu/bioedit/bioedit.html) to retain only sequences where the three XendoU residues whose point mutation abolished catalysis (i.e., H162, H178, K224) are present. The alignment shown in Supplementary Table 1 was edited by hand to minimize the number of deletions occurring within secondary structure elements.
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