Author: Mohd Ropidi, Muhammad Izzuddin; Khazali, Ahmad Suhail; Nor Rashid, Nurshamimi; Yusof, Rohana
Title: Endoplasmic reticulum: a focal point of Zika virus infection Document date: 2020_1_20
ID: 0zr2e8lh_21
Snippet: One of the fundamental roles of the ER is the folding of secreted and membrane proteins, which depends on a multitude of factors including supply of ATPs, stable Ca 2+ concentration, and a balanced redox environment [44] . Disruption of this specialized environment within the ER, whether through glucose deprivation or viral infection, may lead to overwhelming accumulation of misfolded and unfolded proteins-a condition described as ER stress [45] .....
Document: One of the fundamental roles of the ER is the folding of secreted and membrane proteins, which depends on a multitude of factors including supply of ATPs, stable Ca 2+ concentration, and a balanced redox environment [44] . Disruption of this specialized environment within the ER, whether through glucose deprivation or viral infection, may lead to overwhelming accumulation of misfolded and unfolded proteins-a condition described as ER stress [45] .
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