Author: Hercik, Christine; Cosmas, Leonard; Mogeni, Ondari D.; Wamola, Newton; Kohi, Wanze; Houpt, Eric; Liu, Jie; Ochieng, Caroline; Onyango, Clayton; Fields, Barry; Mfinanga, Sayoki; Montgomery, Joel M.
Title: A Combined Syndromic Approach to Examine Viral, Bacterial, and Parasitic Agents among Febrile Patients: A Pilot Study in Kilombero, Tanzania Document date: 2017_12_26
ID: 1br7nhzt_26
Snippet: In addition, for those patients in which we had a microscopy result, we conducted an ANOVA test to examine mean Ct values, as determined by qPCR, for patients grouped within each level of parasite intensity (1+, 2+, 3+, or 4+), as determined by blood smear. Because low Ct values correspond to high parasite loads, we would expect that lower mean Ct values correlate with higher levels of parasite intensity. Results were statistically significant (P.....
Document: In addition, for those patients in which we had a microscopy result, we conducted an ANOVA test to examine mean Ct values, as determined by qPCR, for patients grouped within each level of parasite intensity (1+, 2+, 3+, or 4+), as determined by blood smear. Because low Ct values correspond to high parasite loads, we would expect that lower mean Ct values correlate with higher levels of parasite intensity. Results were statistically significant (P value = 0.0025) and findings demonstrate an inverse relationship between mean Ct values and level of parasite intensity. As depicted in Figure 4 , we observe lower mean Ct values (i.e., higher detected numbers of Plasmodium parasites) correlated with higher levels of parasite intensity.
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