Author: Joshua A. Hayward; Mary Tachedjian; Adam Johnson; Tamsin B. Gordon; Jie Cui; Glenn A. Marsh; Michelle L. Baker; Lin-Fa Wang; Gilda Tachedjian
Title: Bats Possess Unique Variants of the Antiviral Restriction Factor Tetherin Document date: 2020_4_9
ID: eksi9yia_10
Snippet: The predicted T. melanopogon tetherin nucleotide sequence contains two key mutations upstream of its short isoform start site: an ATG to CTG change in the long isoform start codon, and a TAG stop codon in between the two start codon sites, either of which would be sufficient to prevent the production of the long isoform of tetherin. No nucleotide conflicts exist between the 17 reads mapping to this region of the T. melanopogon tetherin sequence, .....
Document: The predicted T. melanopogon tetherin nucleotide sequence contains two key mutations upstream of its short isoform start site: an ATG to CTG change in the long isoform start codon, and a TAG stop codon in between the two start codon sites, either of which would be sufficient to prevent the production of the long isoform of tetherin. No nucleotide conflicts exist between the 17 reads mapping to this region of the T. melanopogon tetherin sequence, indicating that these mutations are unlikely to represent sequencing or consensus alignment errors.
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