Author: Lu, Qing-Bin; Tong, Yi-Gang; Wo, Ying; Wang, Hong-Yu; Liu, En-Mei; Gray, Gregory C; Liu, Wei; Cao, Wu-Chun
Title: Epidemiology of human adenovirus and molecular characterization of human adenovirus 55 in China, 2009–2012 Document date: 2014_1_28
ID: 0jb8vgt9_20
Snippet: The overall evolutionary rates of hexon gene and fiber gene of HAdV-55 were estimated at 6Ã2 9 10 À5 nucleotide substitutions per site per year (s/s/y) (95% HPD: 5Ã5 9 10 À6 -1Ã5 9 10 À4 s/s/y) and 8Ã0 9 10 À5 s/s/y (95% HPD: 6Ã6 9 10 À6 -1Ã8 9 10 À4 s/s/y), respectively. The evolutionary rates were lower (1Ã7 9 10 À5 s/s/y, 95% HPD: 2Ã2 9 10 À9 -3Ã5 9 10 À5 s/s/y) when based on whole genome. The HAdV-55 strains from mainland Ch.....
Document: The overall evolutionary rates of hexon gene and fiber gene of HAdV-55 were estimated at 6Ã2 9 10 À5 nucleotide substitutions per site per year (s/s/y) (95% HPD: 5Ã5 9 10 À6 -1Ã5 9 10 À4 s/s/y) and 8Ã0 9 10 À5 s/s/y (95% HPD: 6Ã6 9 10 À6 -1Ã8 9 10 À4 s/s/y), respectively. The evolutionary rates were lower (1Ã7 9 10 À5 s/s/y, 95% HPD: 2Ã2 9 10 À9 -3Ã5 9 10 À5 s/s/y) when based on whole genome. The HAdV-55 strains from mainland China seems to have diverged from their TMRCA with other strains from Taiwan Province/Singapore/South Dakota around 15 years ago considering the hexon gene ( Figure S3A ), 10 years ago considering the fiber gene ( Figure S3B) , and 35 years ago considering the whole genome ( Figure S3C ), respectively.
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