Author: Schanzer, Dena L.; Garner, Michael J.; Hatchette, Todd F.; Langley, Joanne M.; Aziz, Samina; Tam, Theresa W. S.
Title: Estimating Sensitivity of Laboratory Testing for Influenza in Canada through Modelling Document date: 2009_8_18
ID: 06boh550_17
Snippet: The model estimated sensitivity based on influenza test results reported to the RVDSS of 30-40% is much lower than the standard assay sensitivities documented in the literature. Standard sensitivities for diagnostic procedures used by participating laboratories ranged from 64% for rapid antigen tests to 95% for RT-PCR tests, averaging 75% for the study period [23] . As performance characteristics of specific tests are generally based on high qual.....
Document: The model estimated sensitivity based on influenza test results reported to the RVDSS of 30-40% is much lower than the standard assay sensitivities documented in the literature. Standard sensitivities for diagnostic procedures used by participating laboratories ranged from 64% for rapid antigen tests to 95% for RT-PCR tests, averaging 75% for the study period [23] . As performance characteristics of specific tests are generally based on high quality specimens, the difference of approximately 40% is likely linked to any one of many operational procedures that affects the quality of the specimen and its procurement. Unlike validation studies, our samples are taken from a variety of clinical settings and processed with a variety of procedures across the country. As well, variation in the indications for diagnostic testing may vary across the country.
Search related documents:
Co phrase search for related documents- antigen test and clinical setting: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- antigen test and diagnostic testing: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- antigen test and high quality: 1, 2, 3, 4, 5
- antigen test and performance characteristic: 1, 2, 3
- assay sensitivity and clinical setting: 1, 2, 3, 4, 5, 6, 7, 8, 9
- assay sensitivity and diagnostic procedure: 1, 2, 3, 4
- assay sensitivity and diagnostic testing: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- assay sensitivity and high quality: 1, 2, 3, 4, 5, 6
- assay sensitivity and performance characteristic: 1
- clinical setting and diagnostic procedure: 1
- clinical setting and diagnostic testing: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- clinical setting and high quality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- clinical setting and performance characteristic: 1, 2
- country procedure and diagnostic procedure: 1
- diagnostic procedure and high quality: 1
- diagnostic procedure and literature document: 1
- diagnostic testing and high quality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- diagnostic testing and high quality specimen: 1
- diagnostic testing and performance characteristic: 1
Co phrase search for related documents, hyperlinks ordered by date