Selected article for: "important role and lymphoid tissue"
Author: Oh, Taehwan; Park, Kee Hwan; Yang, Siyeon; Jeong, Jiwoon; Kang, Ikjae; Park, Changhoon; Chae, Chanhee
Title: Evaluation of the efficacy of a trivalent vaccine mixture against a triple challenge with Mycoplasma hyopneumoniae, PCV2, and PRRSV and the efficacy comparison of the respective monovalent vaccines against a single challenge
  • Document date: 2019_10_16
    • ID: 0q0jon8j_31
    Snippet: Three challenge strains were used in this study. These included PRRSV strain SNUVR090851 (PRRSV-2, lineage 1, GenBank JN315685), M. hyopneumoniae strain SNU98703, and PCV2b strain SNUVR000463 (GenBank KF871068). Several key reasons played an important role in defining strain selection. The M. hyopneumoniae (strain SNU98703) produced lesions typical of M. hyopneumoniae found within the peribronchial and peribronchiolar lymphoid tissue hyperplasia .....
    Document: Three challenge strains were used in this study. These included PRRSV strain SNUVR090851 (PRRSV-2, lineage 1, GenBank JN315685), M. hyopneumoniae strain SNU98703, and PCV2b strain SNUVR000463 (GenBank KF871068). Several key reasons played an important role in defining strain selection. The M. hyopneumoniae (strain SNU98703) produced lesions typical of M. hyopneumoniae found within the peribronchial and peribronchiolar lymphoid tissue hyperplasia in the lungs of infected pigs [20] , while the PRRSV (strain SNUVR090851) caused interstitial pneumonia in the lungs of infected pigs [8] , and the PCV2b (strain SNUVR000463) caused mild lymphoid depletion in the lymph nodes of infected pigs [21] . A triple challenge using M. hyopneumoniae (strain SNU98703), PRRSV (strain SNUVR090851), and PCV2b (strain SNUVR000463) also produced similar clinical symptoms [22] .

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