Selected article for: "bayesian posterior probability and posterior probability"
Author: Hünemeier, Tábita; Amorim, Carlos Eduardo Guerra; Azevedo, Soledad; Contini, Veronica; Acuña-Alonzo, Víctor; Rothhammer, Francisco; Dugoujon, Jean-Michel; Mazières, Stephane; Barrantes, Ramiro; Villarreal-Molina, María Teresa; Paixão-Côrtes, Vanessa Rodrigues; Salzano, Francisco M.; Canizales-Quinteros, Samuel; Ruiz-Linares, Andres; Bortolini, Maria Cátira
Title: Evolutionary Responses to a Constructed Niche: Ancient Mesoamericans as a Model of Gene-Culture Coevolution
  • Document date: 2012_6_21
    • ID: 05y53vbg_22
    Snippet: (c.1) ABCA1*230Cys allele age. The ABCA1*230Cys allele age estimates, using population frequency information, were 12,097 YBP and 19,409 YBP, considering data from all populations and only those from Mesoamerica/Central America, respectively. But the allele age obtained using the observed LD and a Bayesian approach, is relatively younger, 7,540 YBP, with a posterior probability of 99%. Although the numbers generated with these two distinct method.....
    Document: (c.1) ABCA1*230Cys allele age. The ABCA1*230Cys allele age estimates, using population frequency information, were 12,097 YBP and 19,409 YBP, considering data from all populations and only those from Mesoamerica/Central America, respectively. But the allele age obtained using the observed LD and a Bayesian approach, is relatively younger, 7,540 YBP, with a posterior probability of 99%. Although the numbers generated with these two distinct methods are compatible with an American origin of the ABCA1*230Cys allele [32] , the last seems more realistic since methods based on LD, rather than frequencies, have the property of reflecting what happened to an allele more accurately [33] . Discrepancies between estimates obtained from these two approaches are usually taken as evidence that selection has increased the frequency of the allele to higher levels than expected by random genetic drift [33, 54] .

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