Author: Zhai, Xiaofeng; Wang, Shilei; Zhu, Mengyan; He, Wei; Pan, Zhongzhou; Su, Shuo
Title: Antiviral Effect of Lithium Chloride and Diammonium Glycyrrhizinate on Porcine Deltacoronavirus In Vitro Document date: 2019_9_9
ID: 1m5yr8uc_21
Snippet: LiCl and DG cytotoxicity in LLC-PK1 cells. The cellular cytotoxic effect of LiCl and DG in LLC-PK1 cells was determined using the CCK8 kit. The structure of DG is shown in Figure 1A . The maximum LiCl and DG concentrations that resulted in a cell viability higher than 80% were 60 mM and 1250 µg/mL, respectively ( Figure 1B ,C). No differences in cell morphology compared to the mock-treated cells were observed (data not shown) at concentrations o.....
Document: LiCl and DG cytotoxicity in LLC-PK1 cells. The cellular cytotoxic effect of LiCl and DG in LLC-PK1 cells was determined using the CCK8 kit. The structure of DG is shown in Figure 1A . The maximum LiCl and DG concentrations that resulted in a cell viability higher than 80% were 60 mM and 1250 µg/mL, respectively ( Figure 1B ,C). No differences in cell morphology compared to the mock-treated cells were observed (data not shown) at concentrations of 60 mM LiCl and 1250 µg/mL DG; therefore, 10-60 mM LiCl and 125-1250 µg/mL DG were used in subsequent antiviral assays.
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