Author: Chenoll, Empar; Casinos, Beatriz; Bataller, Esther; Buesa, Javier; Ramón, Daniel; Genovés, Salvador; Fábrega, Joan; Rivero Urgell, Montserrat; Moreno Muñoz, José A.
Title: Identification of a Peptide Produced by Bifidobacterium longum CECT 7210 with Antirotaviral Activity Document date: 2016_5_4
ID: 0sxl6f1r_3
Snippet: A previous study demonstrated that strain B. longum subsp. infantis CECT 7210 exerts a direct in vitro effect on rotavirus infection in HT-29 and MA-104 cell lines (Muñoz et al., 2011) . Furthermore, an in vivo effect was shown to involve both antiviral effects and immunological enhancement, providing preliminary protection against the rotavirus infection in a mouse model. The strain was also characterized, demonstrating that B. longum subsp. in.....
Document: A previous study demonstrated that strain B. longum subsp. infantis CECT 7210 exerts a direct in vitro effect on rotavirus infection in HT-29 and MA-104 cell lines (Muñoz et al., 2011) . Furthermore, an in vivo effect was shown to involve both antiviral effects and immunological enhancement, providing preliminary protection against the rotavirus infection in a mouse model. The strain was also characterized, demonstrating that B. longum subsp. infantis CECT 7210 fulfills the main criteria required for consideration as a probiotic. However, the interaction of the probiotic with the host cell surface alone did not explain all the mechanisms involved, since infection levels decreased even when the probiotic was added directly to the virus, therefore further studies must be conducted to establish the mechanisms involved in the antiviral effect of this probiotic strain.
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