Author: Kummer, Susann; Avinoam, Ori; Kräusslich, Hans-Georg
Title: IFITM3 Clusters on Virus Containing Endosomes and Lysosomes Early in the Influenza A Infection of Human Airway Epithelial Cells Document date: 2019_6_12
ID: 1345qct4_32
Snippet: Endocytosed material is generally sorted to different destinations: reusable ligands and receptors are returned to the cell surface via recycling endosomes, while the material destined for degradation traffic to lysosomes [65] . Previous studies reported a substantial co-localization between virus-containing compartments and Rme-1 that is thought to be associated with sorting and recycling endosomes [66] . Furthermore, recent reports have suggest.....
Document: Endocytosed material is generally sorted to different destinations: reusable ligands and receptors are returned to the cell surface via recycling endosomes, while the material destined for degradation traffic to lysosomes [65] . Previous studies reported a substantial co-localization between virus-containing compartments and Rme-1 that is thought to be associated with sorting and recycling endosomes [66] . Furthermore, recent reports have suggested that Rab11-associated recycling endosomes are required for vRNP trafficking, assembly, and virion budding at the cellular surface in the late phase of IAV infection [67] [68] [69] [70] .
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