Selected article for: "selectivity index and SI selectivity index"

Author: Natalia Fintelman-Rodrigues; Carolina Q. Sacramento; Carlyle Ribeiro Lima; Franklin Souza da Silva; André C. Ferreira; Mayara Mattos; Caroline S. de Freitas; Vinicius Cardoso Soares; Suelen da Silva Gomes Dias; Jairo R. Temerozo; Milene Miranda; Aline R. Matos; Fernando A. Bozza; Nicolas Carels; Carlos Roberto Alves; Marilda M. Siqueira; Patrícia T. Bozza; Thiago Moreno L. Souza
Title: Atazanavir inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production
  • Document date: 2020_4_5
  • ID: 6zk0ioep_16
    Snippet: Our results indicate that the selectivity index (SI, which represents the ratio between the CC 50 and EC 50 values) for ATV/RTV, ATV and CQ were 560, 156 and 259, respectively, which shows that ATV/RTV has a high therapeutic potential that was greater than CQ......
    Document: Our results indicate that the selectivity index (SI, which represents the ratio between the CC 50 and EC 50 values) for ATV/RTV, ATV and CQ were 560, 156 and 259, respectively, which shows that ATV/RTV has a high therapeutic potential that was greater than CQ.

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