Author: de Silva, Eric; Ferguson, Neil M.; Fraser, Christophe
Title: Inferring pandemic growth rates from sequence data Document date: 2012_8_7
ID: 1piyoafd_13
Snippet: Generations of the simulated epidemic are discrete. In each generation, the number of offspring generated by each sequence of the current generation is evaluated by sampling a negative binomial distribution with mean R (which can potentially change over time) and dispersion parameter k (which is held fixed over time). Each nucleotide of each sequence of the next generation is either inherited directly from its ancestor or mutates from its parent .....
Document: Generations of the simulated epidemic are discrete. In each generation, the number of offspring generated by each sequence of the current generation is evaluated by sampling a negative binomial distribution with mean R (which can potentially change over time) and dispersion parameter k (which is held fixed over time). Each nucleotide of each sequence of the next generation is either inherited directly from its ancestor or mutates from its parent with some probability. If a nucleotide does mutate, which type of substitution occurs is drawn from a substitution matrix derived from the Kimura two-parameter model.
Search related documents:
Co phrase search for related documents- binomial distribution and simulated epidemic: 1
- generation sequence and simulated epidemic: 1
- Kimura parameter model and parameter model: 1, 2, 3, 4, 5, 6, 7
- parameter model and simulated epidemic: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date