Author: Xu, Yingying; Yuen, Pak-Wai; Lam, Jenny Ka-Wing
Title: Intranasal DNA Vaccine for Protection against Respiratory Infectious Diseases: The Delivery Perspectives Document date: 2014_7_10
ID: 0bma2749_17
Snippet: The intranasal route of drug administration has been frequently used to treat local conditions such as nasal congestion and allergy. Intranasal administration is characterized by easy administration, rapid onset of action and avoidance of first-pass metabolism. The needle-free administration route is non-invasive and can avoid the risk of spreading blood-borne infections, which is a particular problem in developing countries. These desirable feat.....
Document: The intranasal route of drug administration has been frequently used to treat local conditions such as nasal congestion and allergy. Intranasal administration is characterized by easy administration, rapid onset of action and avoidance of first-pass metabolism. The needle-free administration route is non-invasive and can avoid the risk of spreading blood-borne infections, which is a particular problem in developing countries. These desirable features lead to the exploration of the systemic delivery of polar drugs or biomolecules including vaccines that are not feasible in other administration routes.
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