Author: Dyer, Wayne B; Zaunders, John J; Yuan, Fang Fang; Wang, Bin; Learmont, Jennifer C; Geczy, Andrew F; Saksena, Nitin K; McPhee, Dale A; Gorry, Paul R; Sullivan, John S
Title: Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection Document date: 2008_12_11
ID: 0ddutmdd_23
Snippet: The loss of non-progressor status was based on increasing viraemia and/or decreasing CD4 counts in 5 of 8, and initiation of ART in these individuals (Additional file 1). Patient C122 lost LTNP status due to gradually increasing viraemia, but died from unrelated causes before substantial T cell loss was observed. Another two elderly individuals (C18 and C54; both SBBC members), each with low detectable viraemia, died before losing their non-progr.....
Document: The loss of non-progressor status was based on increasing viraemia and/or decreasing CD4 counts in 5 of 8, and initiation of ART in these individuals (Additional file 1). Patient C122 lost LTNP status due to gradually increasing viraemia, but died from unrelated causes before substantial T cell loss was observed. Another two elderly individuals (C18 and C54; both SBBC members), each with low detectable viraemia, died before losing their non-progressor status [13, 17] .
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