Author: Ojosnegros, Samuel; Beerenwinkel, Niko
Title: Models of RNA virus evolution and their roles in vaccine design Document date: 2010_11_3
ID: 0q928h3b_51
Snippet: On the epidemiological level, mathematical models of inter-host transmission of a given viral pathogen can predict the portion of individuals within a population that needs to be vaccinated in order to achieve herd immunity (HI). HI occurs if partial vaccination provides protection also to unvaccinated individuals and the population is protected against invasion of the pathogen. The critical proportion of immune individuals above which the diseas.....
Document: On the epidemiological level, mathematical models of inter-host transmission of a given viral pathogen can predict the portion of individuals within a population that needs to be vaccinated in order to achieve herd immunity (HI). HI occurs if partial vaccination provides protection also to unvaccinated individuals and the population is protected against invasion of the pathogen. The critical proportion of immune individuals above which the disease cannot persist is the HI threshold
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