Author: Geng, Lingling; Liu, Zunpeng; Zhang, Weiqi; Li, Wei; Wu, Zeming; Wang, Wei; Ren, Ruotong; Su, Yao; Wang, Peichang; Sun, Liang; Ju, Zhenyu; Chan, Piu; Song, Moshi; Qu, Jing; Liu, Guang-Hui
Title: Chemical screen identifies a geroprotective role of quercetin in premature aging Document date: 2018_8_1
ID: 1mrj6nb3_18
Snippet: To investigate whether Que was directly involved in the regulation of aging biological process, we checked the transcriptional levels of aging and longevity-associated genes annotated by the Human Ageing Genomic Resources (HAGR) database. Gene expression analysis showed that aging and longevity-associated genes were upregulated (P < 0.0001) upon Que treatment ( Fig. 7A-C) . Of note, a series of anti-oxidative genes including GSTP1, GSR and GSTM1.....
Document: To investigate whether Que was directly involved in the regulation of aging biological process, we checked the transcriptional levels of aging and longevity-associated genes annotated by the Human Ageing Genomic Resources (HAGR) database. Gene expression analysis showed that aging and longevity-associated genes were upregulated (P < 0.0001) upon Que treatment ( Fig. 7A-C) . Of note, a series of anti-oxidative genes including GSTP1, GSR and GSTM1
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