Selected article for: "delay clearance and viral clearance"
Author: Xudan Chen; Yang Zhang; Baoyi Zhu; Jianwen Zeng; Wenxin Hong; Xi He; Jingfeng Chen; Haipeng Zheng; Shuang Qiu; Ying Deng; Juliana Chan; Jian Wang
Title: Associations of clinical characteristics and antiviral drugs with viral RNA clearance in patients with COVID-19 in Guangzhou, China: a retrospective cohort study
  • Document date: 2020_4_14
    • ID: 9j4ese89_33
    Snippet: In this study, only 10% of patients received corticosteroid treatment compared to 50%-79% as reported in patients from Wuhan [7, 9] . Our analysis indicated that corticosteroid use was associated with delayed viral RNA clearance, in line with a recent report from Wuhan [18]. This may be due to selection bias since patients with serious/critical illness were more likely to be treated with corticosteroid. Moreover, corticosteroid can suppress the i.....
    Document: In this study, only 10% of patients received corticosteroid treatment compared to 50%-79% as reported in patients from Wuhan [7, 9] . Our analysis indicated that corticosteroid use was associated with delayed viral RNA clearance, in line with a recent report from Wuhan [18]. This may be due to selection bias since patients with serious/critical illness were more likely to be treated with corticosteroid. Moreover, corticosteroid can suppress the immune systemand delay clearance of viral RNA [25], calling for its cautious use in patients with COVID-19.

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