Author: Ganguly, Bhaskar; Umapathi, Vijaypillai; Rastogi, Sunil Kumar
Title: Nitric oxide induced by Indian ginseng root extract inhibits Infectious Bursal Disease virus in chicken embryo fibroblasts in vitro Document date: 2018_1_8
ID: 1pvydc2q_1
Snippet: Infectious Bursal Disease (IBD) is an acute, highly contagious, and immunosuppressive disease of young chicken, caused by double-stranded RNA virus belonging to the genus Avibirnavirus of family Birnaviridae. It is characterized by the destruction of dividing lymphoid cells in the bursa of Fabricius causing cytolysis leading to immunosuppression in addition to severe economic losses due to impaired growth, death, and excessive condemnations of ca.....
Document: Infectious Bursal Disease (IBD) is an acute, highly contagious, and immunosuppressive disease of young chicken, caused by double-stranded RNA virus belonging to the genus Avibirnavirus of family Birnaviridae. It is characterized by the destruction of dividing lymphoid cells in the bursa of Fabricius causing cytolysis leading to immunosuppression in addition to severe economic losses due to impaired growth, death, and excessive condemnations of carcasses because of skeletal muscle hemorrhages [9] . The virus is evolutionarily related to rotaviruses (Reoviridae) and picornaviruses (Picornaviridae) (Dalton and Rodriguez, [8] ). The virus can be adapted to grow and produce cytopathic effects in chicken embryo fibroblasts (CEF) [25] .
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