Selected article for: "genome length and reference database"

Author: Sofia Morfopoulou; Vincent Plagnol
Title: Bayesian mixture analysis for metagenomic community profiling.
  • Document date: 2014_7_25
  • ID: 058r9486_60
    Snippet: where l g is the length of the reference genome, when short reads are matched to a nucleotide database. For nucleotide matching, l g has a large impact on the probability computation. However, when matching against protein databases, the more limited heterogeneity of protein lengths results in a much smaller impact of the length parameter. In addition, incomplete annotation can potentially make the inclusion of protein length problematic for the .....
    Document: where l g is the length of the reference genome, when short reads are matched to a nucleotide database. For nucleotide matching, l g has a large impact on the probability computation. However, when matching against protein databases, the more limited heterogeneity of protein lengths results in a much smaller impact of the length parameter. In addition, incomplete annotation can potentially make the inclusion of protein length problematic for the p ij computation. Consequently, for protein matched sequences, we simply defined our p ij as:

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