Selected article for: "immune response and passive immunization"
Author: Sugiarto, Sarah; Spiri, Andrea M.; Riond, Barbara; Novacco, Marilisa; Oestmann, Angelina; de Miranda, Luisa H. Monteiro; Meli, Marina L.; Boretti, Felicitas S.; Hofmann-Lehmann, Regina; Willi, Barbara
Title: Passive immunization does not provide protection against experimental infection with Mycoplasma haemofelis
  • Document date: 2016_8_5
    • ID: 1uw8xcxw_61
    Snippet: In conclusion, passive immunization did not provide protection against experimental infection with Mhf but instead enhanced RBC fragility and was associated with a more pronounced immune response after infection. This result suggests that a humoral immune response in the absence of cellular immune mechanisms is insufficient to provide protection from Mhf infection. Potential vaccine candidates should include the induction of a cellular immune res.....
    Document: In conclusion, passive immunization did not provide protection against experimental infection with Mhf but instead enhanced RBC fragility and was associated with a more pronounced immune response after infection. This result suggests that a humoral immune response in the absence of cellular immune mechanisms is insufficient to provide protection from Mhf infection. Potential vaccine candidates should include the induction of a cellular immune response against Mhf. and the plasma transfusions. FSB was responsible for the clinical aspects of the study and supported the plasma transfusions of the cats. RHL supported the statistical analyses. SS and BW drafted the manuscript. BW and RHL edited the manuscript. All authors read and approved the final manuscript.

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