Selected article for: "infection cause and viral infection"
Author: Melnik, Lilia I; Garry, Robert F; Morris, Cindy A
Title: Peptide inhibition of human cytomegalovirus infection
  • Document date: 2011_2_22
    • ID: 0p6x4lwx_21
    Snippet: The inhibitory peptides identified here can serve as the basis for the development of a novel therapeutic against HCMV. These antiviral agents could be used as an antiviral treatment to reduce the viral load in pregnant women and neonates. It is not clear how HCMV infects the fetus during pregnancy, but some studies demonstrate that placental infection with HCMV occurs before the transmission of the virus to the fetus and suggest that the placent.....
    Document: The inhibitory peptides identified here can serve as the basis for the development of a novel therapeutic against HCMV. These antiviral agents could be used as an antiviral treatment to reduce the viral load in pregnant women and neonates. It is not clear how HCMV infects the fetus during pregnancy, but some studies demonstrate that placental infection with HCMV occurs before the transmission of the virus to the fetus and suggest that the placenta plays a role in vertical transmission of HCMV from mother to fetus. Also, placental viral infection has been implicated in spontaneous abortion during early pregnancy that occurs in fifteen percent of women with primary HCMV infection. Placental pathology as a result of HCMV infection during pregnancy may also cause premature delivery, intrauterine growth restriction (IUGR), or pre-eclampsia [51] [52] [53] [54] .

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