Peptide inhibition of human cytomegalovirus infection

Melnik, Lilia I; Garry, Robert F; Morris, Cindy A

The class III domain nomenclature used here can apply to both class II and class III viral fusion proteins: domain I (green), domain II (yellow), domain III (blue), domain IV (stem domain, indigo) ( Figure 1 ). This unified nomenclature assigns domain II appellation to the following: VSV G domain IV in the nomenclature of Roche et al. [30] , HSV-1 gB-1 and baculovirus gp64 domain I in the nomenclature of Heldwein et al. [28] and Kadlec et al. [31] as the class III fusion domain, which is structurally similar to class II viral fusion proteins. In addition to minor adjustments in the ends of domains, the current class III viral fusion protein numbering also combines two interacting domains into domain III (I + II in Roche's VSV G nomenclature, III + IV in Heldwein's HSV-1 gB-1 nomenclature and Kadlec's baculovirus nomenclature).