Author: Le-Viet, Nhiem; Le, Viet-Nho; Chung, Hai; Phan, Duc-Tuan; Phan, Quang-Duong; Cao, Thanh-Van; Abat, Cédric; Raoult, Didier; Parola, Philippe
Title: Prospective case-control analysis of the aetiologies of acute undifferentiated fever in Vietnam Document date: 2019_3_4
ID: 0uwm4dk9_31
Snippet: Moreover, among the 12 patients presenting with an eschar in our study, 10 rickettsial infection cases were confirmed (nine cases of O. tsutsugamushi and one case of R. felis infection), and two remaining cases were clinically suspected rickettsial infections. All 12 patients were completely recovered after a doxycycline course. In fact, the diagnostic tools for detecting infectious aetiologies are insufficient in almost all hospitals in Vietnam .....
Document: Moreover, among the 12 patients presenting with an eschar in our study, 10 rickettsial infection cases were confirmed (nine cases of O. tsutsugamushi and one case of R. felis infection), and two remaining cases were clinically suspected rickettsial infections. All 12 patients were completely recovered after a doxycycline course. In fact, the diagnostic tools for detecting infectious aetiologies are insufficient in almost all hospitals in Vietnam and other developing countries; therefore, clinicians treating a patient with fever and eschar should not delay prescribing doxycycline against rickettsial agents. When diagnosing a patient with AUF, a careful examination focusing on the occurrence of eschar, rash, and abnormal aminotransferase levels might increase the precision of rickettsial infection diagnosis.
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