Author: Pinheiro, Aruanã Joaquim Matheus Costa Rodrigues; Gonçalves, Jaciara Sá; Dourado, Ádylla Wilenna Alves; de Sousa, Eduardo Martins; Brito, Natilene Mesquita; Silva, Lanna Karinny; Batista, Marisa Cristina Aranha; de Sá, Joicy Cortez; Monteiro, Cinara Regina Aragão Vieira; Fernandes, Elizabeth Soares; Monteiro-Neto, Valério; Campbell, Lee Ann; Zago, Patrícia Maria Wiziack; Lima-Neto, Lidio Gonçalves
Title: Punica granatum L. Leaf Extract Attenuates Lung Inflammation in Mice with Acute Lung Injury Document date: 2018_2_20
ID: 0e9lq1b5_37
Snippet: Extracts prepared from pomegranate peels and seeds were described previously to possess anti-inflammatory properties [12, 13] . However, very little is known about the effects of pomegranate leaf extracts or fractions on inflammation. We recently demonstrated that the pomegranate leaf hydroalcoholic extract attenuates LPS-induced peritonitis by decreasing the accumulation of leukocytes and the release of proinflammatory mediators in the peritoneu.....
Document: Extracts prepared from pomegranate peels and seeds were described previously to possess anti-inflammatory properties [12, 13] . However, very little is known about the effects of pomegranate leaf extracts or fractions on inflammation. We recently demonstrated that the pomegranate leaf hydroalcoholic extract attenuates LPS-induced peritonitis by decreasing the accumulation of leukocytes and the release of proinflammatory mediators in the peritoneum [8] . We now show that EAFPg protects mice from ALI by reducing lung inflammation.
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