Author: Pinheiro, Aruanã Joaquim Matheus Costa Rodrigues; Gonçalves, Jaciara Sá; Dourado, Ádylla Wilenna Alves; de Sousa, Eduardo Martins; Brito, Natilene Mesquita; Silva, Lanna Karinny; Batista, Marisa Cristina Aranha; de Sá, Joicy Cortez; Monteiro, Cinara Regina Aragão Vieira; Fernandes, Elizabeth Soares; Monteiro-Neto, Valério; Campbell, Lee Ann; Zago, Patrícia Maria Wiziack; Lima-Neto, Lidio Gonçalves
                    Title: Punica granatum L. Leaf Extract Attenuates Lung Inflammation in Mice with Acute Lung Injury  Document date: 2018_2_20
                    ID: 0e9lq1b5_42
                    
                    Snippet: TNF-α induces the expression of adhesion molecules on endothelial cells, thus contributing to neutrophil migration. In ALI, neutrophils are the first cells to be recruited into the lungs [17] . In the present study, we demonstrated that EAFPg reduces neutrophil migration into the alveoli. Accordingly, Bachoual et al. [18] showed that an aqueous extract of P. granatum peel inhibits neutrophil-mediated myeloperoxidase activity and attenuates LPS-i.....
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: TNF-α induces the expression of adhesion molecules on endothelial cells, thus contributing to neutrophil migration. In ALI, neutrophils are the first cells to be recruited into the lungs [17] . In the present study, we demonstrated that EAFPg reduces neutrophil migration into the alveoli. Accordingly, Bachoual et al. [18] showed that an aqueous extract of P. granatum peel inhibits neutrophil-mediated myeloperoxidase activity and attenuates LPS-induced lung inflammation in mice. In addition, Marques et al. [8] showed that the numbers of peritoneal leukocytes, especially neutrophils, are reduced in hydroalcoholic extract-treated rats with acute peritonitis.
 
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