Selected article for: "large scale screening and scale screening"
Author: Guo, Jiao; Jia, Xiaoying; Liu, Yang; Wang, Shaobo; Cao, Junyuan; Zhang, Bo; Xiao, Gengfu; Wang, Wei
Title: Screening of Natural Extracts for Inhibitors against Japanese Encephalitis Virus Infection
  • Document date: 2020_2_21
    • ID: 161ck1i9_1
    Snippet: Optimization of HCS assay conditions. The HCS assay-optimized conditions contain cell density, infective dose, and assay endpoint. The assay conditions for HCS were optimized as follows: cell density of 10,000 cells per 96-well plate, a multiplicity of infection (MOI) of 0.8, and an endpoint of 24 h postinfection. The signal-to-basal (S/B) ratio, coefficient of variation (CV), and Z factor were 2,177, 8.9%, and 0.72, respectively, which demonstra.....
    Document: Optimization of HCS assay conditions. The HCS assay-optimized conditions contain cell density, infective dose, and assay endpoint. The assay conditions for HCS were optimized as follows: cell density of 10,000 cells per 96-well plate, a multiplicity of infection (MOI) of 0.8, and an endpoint of 24 h postinfection. The signal-to-basal (S/B) ratio, coefficient of variation (CV), and Z factor were 2,177, 8.9%, and 0.72, respectively, which demonstrated that the assay was robust and reproductive for the large-scale screening of novel antiviral compounds against JEV infection.

    Search related documents:
    Co phrase search for related documents
    • antiviral compound and large scale: 1, 2, 3, 4, 5
    • assay endpoint and infective dose: 1
    • assay endpoint and large scale: 1
    • assay endpoint infective dose and infective dose: 1, 2
    • assay optimize and large scale: 1, 2, 3
    • cell density and CV variation: 1, 2, 3
    • cell density and CV variation coefficient: 1, 2, 3
    • cell density and infection multiplicity: 1, 2
    • cell density and large scale: 1, 2, 3, 4
    • CV variation and infective dose: 1
    • CV variation and large scale: 1, 2
    • CV variation coefficient and infective dose: 1
    • CV variation coefficient and large scale: 1, 2
    • HCS assay and JEV infection: 1, 2
    • infection multiplicity and JEV infection: 1