Author: Hustedt, Joshua W.; Christie, Celia; Hustedt, Madison M.; Esposito, Daina; Vazquez, Marietta
Title: Seroepidemiology of Human Bocavirus Infection in Jamaica Document date: 2012_5_29
ID: 19k8ed4x_20
Snippet: While HBoV seroepidemiology and prevalence studies have shown evidence for widespread exposure to the virus, the causative role of HBoV in respiratory tract disease is still under investigation. Definitive evidence is difficult to obtain without an in vitro culture system and animal model. While there has been one recent successful report of propagation of HBoV in cell culture, this technique has proven difficult to replicate [32] . In the absenc.....
Document: While HBoV seroepidemiology and prevalence studies have shown evidence for widespread exposure to the virus, the causative role of HBoV in respiratory tract disease is still under investigation. Definitive evidence is difficult to obtain without an in vitro culture system and animal model. While there has been one recent successful report of propagation of HBoV in cell culture, this technique has proven difficult to replicate [32] . In the absence of definitive evidence, comparative studies have been used to suggest a causative role of HBoV in acute infection. However, these studies are complicated by the fact that HBoV is often co-detected with other respiratory viruses, which makes it difficult to draw conclusions about its pathogenicity.
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