Selected article for: "cell surface and cytosol release"
Author: Martinez-Martin, Nadia
Title: Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions
  • Document date: 2017_2_22
    • ID: 1giy1fow_7
    Snippet: Monoclonal antibodies and cDNA libraries CAR identified as a common entry receptor for adenovirus 2/5 and coxsackievirus B [40] Sindbis virus siRNA screens NRAMP as cell surface receptor for entry into Drosophila cells [41] Murine norovirus CRISPR/Cas9 CD300lf identified as a cell surface receptor that determines virus tropism [42] Bacterial distending toxins (E. coli) Haploid cell screens Sphingomyelin synthase 1 and the putative G protein-coupl.....
    Document: Monoclonal antibodies and cDNA libraries CAR identified as a common entry receptor for adenovirus 2/5 and coxsackievirus B [40] Sindbis virus siRNA screens NRAMP as cell surface receptor for entry into Drosophila cells [41] Murine norovirus CRISPR/Cas9 CD300lf identified as a cell surface receptor that determines virus tropism [42] Bacterial distending toxins (E. coli) Haploid cell screens Sphingomyelin synthase 1 and the putative G protein-coupled receptor TMEM181 identified as toxin receptors [43, 44] Clostridium difficile and perfringens toxins Haploid cell screens Lipolysis-stimulated lipoprotein and the low-density lipoprotein receptor-related protein 1 identified as the receptors for the bacterial toxins, respectively [45, 46] Ebola virus Haploid cell screens HOPS proteins and the Niemann-Pick C1 (NCP1) transporter identified as endosomal receptors that mediate cytosol access [47] Lassa virus Haploid cell screens LAMP1, lysosomal-associated membrane protein 1 identified as an essential host factor mediating virus release to cytosol [48] Adeno-associated virus (AAV) serotype 2

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