Author: Andrabi, Raiees; Pallesen, Jesper; Allen, Joel D.; Song, Ge; Zhang, Jinsong; de Val, Natalia; Gegg, Gavin; Porter, Katelyn; Su, Ching-Yao; Pauthner, Matthias; Newman, Amanda; Bouton-Verville, Hilary; Garces, Fernando; Wilson, Ian A.; Crispin, Max; Hahn, Beatrice H.; Haynes, Barton F.; Verkoczy, Laurent; Ward, Andrew B.; Burton, Dennis R.
Title: The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template Document date: 2019_5_21
ID: 1ni7949q_40
Snippet: Overall, the analysis of the immune responses revealed that, due to the extraordinary conservation of the V2-apex bnAb epitope region between HIV and chimpanzee SIV, the MT145K trimer successfully primed human V2-apex bnAb UCA-encoding mouse B cells and induced a V2-focused cross-neutralizing HIV Env-specific response that could be further boosted by HIV Env-derived trimers......
Document: Overall, the analysis of the immune responses revealed that, due to the extraordinary conservation of the V2-apex bnAb epitope region between HIV and chimpanzee SIV, the MT145K trimer successfully primed human V2-apex bnAb UCA-encoding mouse B cells and induced a V2-focused cross-neutralizing HIV Env-specific response that could be further boosted by HIV Env-derived trimers.
Search related documents:
Co phrase search for related documents- Env specific response and immune response: 1
- human prime and immune response: 1
Co phrase search for related documents, hyperlinks ordered by date