Selected article for: "amino acid and good agreement"

Author: Mathew, Suneeth F.; Crowe-McAuliffe, Caillan; Graves, Ryan; Cardno, Tony S.; McKinney, Cushla; Poole, Elizabeth S.; Tate, Warren P.
Title: The Highly Conserved Codon following the Slippery Sequence Supports -1 Frameshift Efficiency at the HIV-1 Frameshift Site
  • Document date: 2015_3_25
  • ID: 10p3mth2_42
    Snippet: We observed a 4-fold decrease in −1 PRF efficiency from 10% with a GGG intercodon to 2.5% with the substituted UGA intercodon when eRF1 was over-expressed. This implies that a significant number of the HIV-1 frameshifting events could be occurring when the intercodon is in the ribosomal decoding (A) site. This is in good agreement with the semi-quantitative amino acid sequencing data discussed above [3] , [60] , [61] ......
    Document: We observed a 4-fold decrease in −1 PRF efficiency from 10% with a GGG intercodon to 2.5% with the substituted UGA intercodon when eRF1 was over-expressed. This implies that a significant number of the HIV-1 frameshifting events could be occurring when the intercodon is in the ribosomal decoding (A) site. This is in good agreement with the semi-quantitative amino acid sequencing data discussed above [3] , [60] , [61] .

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