Author: Russell, Beth; Moss, Charlotte; Rigg, Anne; Van Hemelrijck, Mieke
Title: COVID-19 and treatment with NSAIDs and corticosteroids: should we be limiting their use in the clinical setting? Document date: 2020_3_30
ID: 0uengr9t_6
Snippet: The only other study to investigate NSAID was one which looked at indomethacin, which is commonly prescribed for treatment of gout and arthritis [11] . This study suggested that indomethacin exhibited potent antiviral activity against canine coronavirus in vitro, by dramatically inhibiting virus replication and protecting the host cell from virus-induced damage. Critically, this activity was also observed in vivo and against human SARS-CoV at a c.....
Document: The only other study to investigate NSAID was one which looked at indomethacin, which is commonly prescribed for treatment of gout and arthritis [11] . This study suggested that indomethacin exhibited potent antiviral activity against canine coronavirus in vitro, by dramatically inhibiting virus replication and protecting the host cell from virus-induced damage. Critically, this activity was also observed in vivo and against human SARS-CoV at a concentration dose of 1 mg/kg.
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