Author: van Rijn, Anneloes L.; van Boheemen, Sander; Sidorov, Igor; Carbo, Ellen C.; Pappas, Nikos; Mei, Hailiang; Feltkamp, Mariet; Aanerud, Marianne; Bakke, Per; Claas, Eric C. J.; Eagan, Tomas M.; Hiemstra, Pieter S.; Kroes, Aloys C. M.; de Vries, Jutte J. C.
Title: The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease Document date: 2019_10_24
ID: 0rupk21u_52
Snippet: The sensitivity, specificity and positive and negative predictive values of mNGS were high: 96%, 100%, 82% and 100%, respectively, when encountering a cut-off of �5normalized reads, with a detection limit of approximately Cq 38. The high negative predictive value implicates the potential of mNGS to exclude the most prevalent viral respiratory infections in one test. The potential to exclude any infectious cause, both viral and bacterial, would .....
Document: The sensitivity, specificity and positive and negative predictive values of mNGS were high: 96%, 100%, 82% and 100%, respectively, when encountering a cut-off of �5normalized reads, with a detection limit of approximately Cq 38. The high negative predictive value implicates the potential of mNGS to exclude the most prevalent viral respiratory infections in one test. The potential to exclude any infectious cause, both viral and bacterial, would have significant consequences for starting and/or continuation of antimicrobial or, at the other end of the spectrum, immune-modulating treatment.
Search related documents:
Co phrase search for related documents- detection limit and infectious cause: 1
- detection limit and negative predictive value: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
- detection limit and predictive value: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- detection limit and respiratory infection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38
- detection limit and viral respiratory infection: 1, 2, 3, 4, 5, 6
- high negative predictive value and negative predictive value: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- high negative predictive value and predictive value: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- high negative predictive value and respiratory infection: 1, 2, 3, 4, 5
- immune modulating and infectious cause: 1
- immune modulating and respiratory infection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- immune modulating and viral respiratory infection: 1, 2, 3, 4
- immune modulating treatment and infectious cause: 1
- immune modulating treatment and respiratory infection: 1, 2
- infectious cause and mngs potential: 1
Co phrase search for related documents, hyperlinks ordered by date