Author: Meier, Anita F.; Suter, Mark; Schraner, Elisabeth M.; Humbel, Bruno M.; Tobler, Kurt; Ackermann, Mathias; Laimbacher, Andrea S.
Title: Transfer of Anti-Rotavirus Antibodies during Pregnancy and in Milk Following Maternal Vaccination with a Herpes Simplex Virus Type-1 Amplicon Vector Document date: 2017_2_16
ID: 09hmet7r_25
Snippet: We conclude, that RV specific IgG antibody transfer via the placental route occurred. Moreover, the level of antibody had to be maintained by the lactogenic route by immunized dams or substituted for naïve pups by milk from immunized dams ( Figure 3E ). In conclusion, we were able to show that injection of the sWa[VP2/6/7] amplicon vector raises a RV specific immune response, detected as IgG in sera as well as in milk of immunized animals and th.....
Document: We conclude, that RV specific IgG antibody transfer via the placental route occurred. Moreover, the level of antibody had to be maintained by the lactogenic route by immunized dams or substituted for naïve pups by milk from immunized dams ( Figure 3E ). In conclusion, we were able to show that injection of the sWa[VP2/6/7] amplicon vector raises a RV specific immune response, detected as IgG in sera as well as in milk of immunized animals and that this response is passed to the offspring via both the placental and the lactogenic route.
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