Design and Validation with Influenza A Virus of an Aerosol Transmission Chamber for Ferrets

Turgeon, Nathalie; Hamelin, Marie-Ève; Verreault, Daniel; Lévesque, Ariane; Rhéaume, Chantal; Carbonneau, Julie; Checkmahomed, Liva; Girard, Matthieu; Boivin, Guy; Duchaine, Caroline

icles on the polycarbonate door. A particle separator module was designed to intercept large particles by impaction while letting smaller particles flow through. The separator is composed of a stainless steel plate with 160 orifices distributed in four rows of 40 orifices ( Figure 5A ). Each orifice is 6.4 mm deep and 5 mm in diameter. An impaction plate is located 5 mm from the outlet of each orifice. The velocity of the airborne particles increases as the air from cage number two is forced into cage number three through the orifices of the particle separation module by a suction pump placed upstream of cage number three. Larger particles are impacted on the impaction plates and smaller particles follow the air stream into cage number three (Figure 5b ). A particle separator module was designed to intercept large particles by impaction while letting smaller particles flow through. The separator is composed of a stainless steel plate with 160 orifices distributed in four rows of 40 orifices ( Figure 5A ). Each orifice is 6.4 mm deep and 5 mm in diameter. An impaction plate is located 5 mm from the outlet of each orifice. The velocity of the airborne particles increases as the air from cage number two is forced into cage number three through the orifices of the particle separation module by a suction pump placed upstream of cage number three. Larger particles are impacted on the impaction plates and smaller particles follow the air stream into cage number three ( Figure 5b ). A particle separator module was designed to intercept large particles by impaction while letting smaller particles flow through. The separator is composed of a stainless steel plate with 160 orifices distributed in four rows of 40 orifices ( Figure 5A ). Each orifice is 6.4 mm deep and 5 mm in diameter. An impaction plate is located 5 mm from the outlet of each orifice. A particle separator module was designed to intercept large particles by impaction while letting smaller particles flow through. The separator is composed of a stainless steel plate with 160 orifices distributed in four rows of 40 orifices ( Figure 5A ). Each orifice is 6.4 mm deep and 5 mm in diameter. An impaction plate is located 5 mm from the outlet of each orifice. The velocity of the airborne particles increases as the air from cage number two is forced into cage number three through the orifices of the particle separation module by a suction pump placed upstream of cage number three. Larger particles are impacted on the impaction plates and smaller particles follow the air stream into cage number three (Figure 5b ). The velocity of the airborne particles increases as the air from cage number two is forced into cage number three through the orifices of the particle separation module by a suction pump placed upstream of cage number three. Larger particles are impacted on the impaction plates and smaller particles follow the air stream into cage number three (Figure 5b) .