Author: Okeke, Malachy I.; Okoli, Arinze S.; Diaz, Diana; Offor, Collins; Oludotun, Taiwo G.; Tryland, Morten; Bøhn, Thomas; Moens, Ugo
Title: Hazard Characterization of Modified Vaccinia Virus Ankara Vector: What Are the Knowledge Gaps? Document date: 2017_10_29
ID: 175igdfk_1
Snippet: Vaccines and vaccine vectors are termed genetically modified (GM) if recombinant gene technology is used to create the vaccine or vector. Genetically modified viruses (GMVs) or virus vectors of homologous or heterologous disease antigens are considered highly desirable for vaccinations against diseases that are difficult to treat or for which there exists no effective conventional vaccine, e.g., acquired immune deficiency syndrome (AIDS), malaria.....
Document: Vaccines and vaccine vectors are termed genetically modified (GM) if recombinant gene technology is used to create the vaccine or vector. Genetically modified viruses (GMVs) or virus vectors of homologous or heterologous disease antigens are considered highly desirable for vaccinations against diseases that are difficult to treat or for which there exists no effective conventional vaccine, e.g., acquired immune deficiency syndrome (AIDS), malaria, tuberculosis and neoplastic disorders. Some of the advantages of GMVs in vaccination are the enhancement of immunogenicity without an
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