Author: Qingyang Xu; Shomesh Chaudhuri; Danying Xiao; Andrew W Lo
Title: Bayesian Adaptive Clinical Trials for Anti-Infective Therapeutics during Epidemic Outbreaks Document date: 2020_4_14
ID: 20hk99h4_49
Snippet: The results for the dynamic transmission model with 3, 1.5, 3 weeks and 1 week are summarized in Table 3 . For COVID-19 (rows 3 and 6), we find that the Bayesian optimal sample size and Type I error rate of the dynamic transmission model lie in between the scenarios 2 and 4. This suggests that timely and effective government interventions will protect more subjects from infection and allow more time for the RCT......
Document: The results for the dynamic transmission model with 3, 1.5, 3 weeks and 1 week are summarized in Table 3 . For COVID-19 (rows 3 and 6), we find that the Bayesian optimal sample size and Type I error rate of the dynamic transmission model lie in between the scenarios 2 and 4. This suggests that timely and effective government interventions will protect more subjects from infection and allow more time for the RCT.
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