Author: Vidaña, Beatriz; Martínez, Jorge; Martínez-Orellana, Pamela; García Migura, Lourdes; Montoya, María; Martorell, Jaime; Majó, Natàlia
Title: Heterogeneous pathological outcomes after experimental pH1N1 influenza infection in ferrets correlate with viral replication and host immune responses in the lung Document date: 2014_8_28
ID: 0hyg403m_29
Snippet: Of these four animals, one animal infected with the R11 virus died at 4 dpi, and one animal infected with the R61 virus had to be sacrificed at 4 dpi for ethical reasons. Animals showing more severe clinical signs also presented higher body weight loss (data not shown) which also correlated with more severe pathological findings in the lungs. Temperature was not affected by viral group or by disease severity (data not shown)......
Document: Of these four animals, one animal infected with the R11 virus died at 4 dpi, and one animal infected with the R61 virus had to be sacrificed at 4 dpi for ethical reasons. Animals showing more severe clinical signs also presented higher body weight loss (data not shown) which also correlated with more severe pathological findings in the lungs. Temperature was not affected by viral group or by disease severity (data not shown).
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