Author: Oude Munnink, Bas B; Canuti, Marta; Deijs, Martin; de Vries, Michel; Jebbink, Maarten F; Rebers, Sjoerd; Molenkamp, Richard; van Hemert, Formijn J; Chung, Kevin; Cotten, Matthew; Snijders, Fransje; Sol, Cees JA; van der Hoek, Lia
Title: Unexplained diarrhoea in HIV-1 infected individuals Document date: 2014_1_13
ID: 0e9l19kp_43
Snippet: Remarkably, the prevalence of Aichi virus in our study population was 20%, while previous studies only showed a prevalence of 0.5-1.6% [19, 46] . It could be that the virus is more frequently present in patients with immunodeficiency. Furthermore, the sensitivity of our assay may also play a part. In our study a very sensitive nested PCR assay was used which enables detection of the virus even if it is present at low concentrations. To exclude th.....
Document: Remarkably, the prevalence of Aichi virus in our study population was 20%, while previous studies only showed a prevalence of 0.5-1.6% [19, 46] . It could be that the virus is more frequently present in patients with immunodeficiency. Furthermore, the sensitivity of our assay may also play a part. In our study a very sensitive nested PCR assay was used which enables detection of the virus even if it is present at low concentrations. To exclude that the high prevalence was caused by PCR contamination, all positive PCR products were sequenced. Variation between the viruses from different patients was observed, thereby excluding contamination by a single source (see nucleotide alignments in Additional file 1: Table S3 ).
Search related documents:
Co phrase search for related documents- additional file and high prevalence: 1, 2
- additional file and PCR assay: 1, 2, 3, 4, 5
- additional file and previous study: 1, 2, 3
- additional file and study population: 1, 2, 3, 4, 5, 6, 7, 8, 9
- Aichi virus and high prevalence: 1, 2
- Aichi virus and PCR assay: 1
- Aichi virus and previous study: 1
- Aichi virus and virus detection: 1, 2, 3, 4
- assay sensitivity and different patient: 1, 2
- assay sensitivity and high prevalence: 1, 2, 3, 4, 5, 6, 7, 8, 9
- assay sensitivity and low concentration: 1, 2
- assay sensitivity and nucleotide alignment: 1
- assay sensitivity and PCR assay: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75
- assay sensitivity and PCR product: 1, 2, 3
- assay sensitivity and previous study: 1, 2, 3
- assay sensitivity and study population: 1, 2, 3, 4, 5, 6
- assay sensitivity and virus detection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- different patient and high prevalence: 1, 2, 3
- different patient and immunodeficiency patient: 1
Co phrase search for related documents, hyperlinks ordered by date