Author: Cauchemez, Simon; Epperson, Scott; Biggerstaff, Matthew; Swerdlow, David; Finelli, Lyn; Ferguson, Neil M.
Title: Using Routine Surveillance Data to Estimate the Epidemic Potential of Emerging Zoonoses: Application to the Emergence of US Swine Origin Influenza A H3N2v Virus Document date: 2013_3_5
ID: 16c8dwfq_33
Snippet: We apply our method to assess the human-to-human transmissibility of swine-origin influenza A variant (H1N1v, H1N2v, and H3N2v) virus, in particular that of the H3N2v-M virus with data collected up to December 2011. From December 2005 until December 2011, a total of 27 human clusters of swine-origin influenza A variant virus infections were investigated by the CDC in the US. In clusters caused by the H3N2v-M virus, three of six (50%) of the first.....
Document: We apply our method to assess the human-to-human transmissibility of swine-origin influenza A variant (H1N1v, H1N2v, and H3N2v) virus, in particular that of the H3N2v-M virus with data collected up to December 2011. From December 2005 until December 2011, a total of 27 human clusters of swine-origin influenza A variant virus infections were investigated by the CDC in the US. In clusters caused by the H3N2v-M virus, three of six (50%) of the first detected cases were infected by swine compared with 17 of 21 (81%) in clusters caused by the other variant viruses (Table 1) . Table 1 gives R estimates for different assumptions about the case detection rate r and overdispersion parameter k.
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