Author: Wang, Ting; Yin, Huiquan; Li, Yan; Zhao, Lingxiao; Sun, Xiahui; Cong, Hua
Title: Vaccination with recombinant adenovirus expressing multi-stage antigens of Toxoplasma gondii by the mucosal route induces higher systemic cellular and local mucosal immune responses than with other vaccination routes Document date: 2017_4_3
ID: 1ay8y7li_6
Snippet: All the experimental procedures with animals used in the present study were granted prior approval by the Institutional Animal Care and Use Committee of Shandong University under Contract LL201602044. Humane endpoints are chosen to terminate the pain or distress of the experimental animals via euthanasia. Mice were monitored daily over 11 weeks for signs of toxoplasmosis including food and water intake difficulties, fatigue, severe ascites, and a.....
Document: All the experimental procedures with animals used in the present study were granted prior approval by the Institutional Animal Care and Use Committee of Shandong University under Contract LL201602044. Humane endpoints are chosen to terminate the pain or distress of the experimental animals via euthanasia. Mice were monitored daily over 11 weeks for signs of toxoplasmosis including food and water intake difficulties, fatigue, severe ascites, and any test animals that showed signs of illness were euthanized immediately with CO 2 gas.
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