Author: Kolodziejek, Jolanta; Seidel, Bernhard; Jungbauer, Christof; Dimmel, Katharina; Kolodziejek, Michael; Rudolf, Ivo; Hubálek, Zdenek; Allerberger, Franz; Nowotny, Norbert
Title: West Nile Virus Positive Blood Donation and Subsequent Entomological Investigation, Austria, 2014 Document date: 2015_5_11
ID: 0vm2hhdr_24
Snippet: To explore the pathogenicity and neuroinvasiveness markers of the newly determined WNV strains, predicted N-glycosylation sites of the relevant viral proteins E [13] , [14] and NS1 [15] were analyzed using the program NetNGlyc 1.0 (http://www.cbs.dtu.dk/services/ NetNGlyc/). Certain amino acids (P249 in NS3 and P250 in NS1) assumed to be associated with increased virulence were explored according to [16] and [17] , respectively, summarized in [18.....
Document: To explore the pathogenicity and neuroinvasiveness markers of the newly determined WNV strains, predicted N-glycosylation sites of the relevant viral proteins E [13] , [14] and NS1 [15] were analyzed using the program NetNGlyc 1.0 (http://www.cbs.dtu.dk/services/ NetNGlyc/). Certain amino acids (P249 in NS3 and P250 in NS1) assumed to be associated with increased virulence were explored according to [16] and [17] , respectively, summarized in [18] . Ability for neuroinvasiveness was furthermore investigated by laboratory mice experiments as described above (see section Virus isolation).
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